Targeted regulation of TAK1 counteracts dystrophinopathy in a DMD mouse model

Muscular dystrophies make up a group of genetic neuromuscular disorders that involve severe muscle wasting. TGF-β–activated kinase 1 (TAK1) is an important signaling protein that regulates cell survival, growth, and inflammation. TAK1 has been recently found to promote myofiber growth in the skeleta...

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Detalles Bibliográficos
Autores principales: Roy, Anirban, Koike, Tatiana E., Joshi, Aniket S., Tomaz da Silva, Meiricris, Mathukumalli, Kavya, Wu, Mingfu, Kumar, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322678/
https://www.ncbi.nlm.nih.gov/pubmed/37071470
http://dx.doi.org/10.1172/jci.insight.164768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322678/
https://www.ncbi.nlm.nih.gov/pubmed/37071470
http://dx.doi.org/10.1172/jci.insight.164768

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