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Atomistic simulations of the Escherichia coli ribosome provide selection criteria for translationally active substrates
As genetic code expansion advances beyond l-α-amino acids to backbone modifications and new polymerization chemistries, delineating what substrates the ribosome can accommodate remains a challenge. The Escherichia coli ribosome tolerates non-l-α-amino acids in vitro, but few structural insights that...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322701/ https://www.ncbi.nlm.nih.gov/pubmed/37308707 http://dx.doi.org/10.1038/s41557-023-01226-w |