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Injury prevents Ras mutant cell expansion in mosaic skin

Healthy skin is a mosaic of wild-type and mutant clones(1,2). Although injury can cooperate with mutated Ras family proteins to promote tumorigenesis(3–12), the consequences in genetically mosaic skin are unknown. Here we show that after injury, wild-type cells suppress aberrant growth induced by on...

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Detalles Bibliográficos
Autores principales: Gallini, Sara, Annusver, Karl, Rahman, Nur-Taz, Gonzalez, David G., Yun, Sangwon, Matte-Martone, Catherine, Xin, Tianchi, Lathrop, Elizabeth, Suozzi, Kathleen C., Kasper, Maria, Greco, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322723/
https://www.ncbi.nlm.nih.gov/pubmed/37344586
http://dx.doi.org/10.1038/s41586-023-06198-y