Standard-dose versus double-dose dolutegravir in HIV-associated tuberculosis in South Africa (RADIANT-TB): a phase 2, non-comparative, randomised controlled trial

BACKGROUND: The drug–drug interaction between rifampicin and dolutegravir can be overcome by supplemental dolutegravir dosing, which is difficult to implement in high-burden settings. We aimed to test whether virological outcomes with standard-dose dolutegravir-based antiretroviral therapy (ART) are...

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Detalles Bibliográficos
Autores principales: Griesel, Rulan, Zhao, Ying, Simmons, Bryony, Omar, Zaayid, Wiesner, Lubbe, Keene, Claire M, Hill, Andrew M, Meintjes, Graeme, Maartens, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322729/
https://www.ncbi.nlm.nih.gov/pubmed/37230101
http://dx.doi.org/10.1016/S2352-3018(23)00081-4

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