The tumor suppressor CREBBP and the oncogene MYCN cooperate to induce malignant brain tumors in mice

The tumor suppressor and chromatin modifier cAMP response element-binding protein binding protein (CREBBP) and v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (MYCN), a member of the MYC oncogene family, are critically involved in brain development. Both genes are frequentl...

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Detalles Bibliográficos
Autores principales: Schoof, Melanie, Epplen, Gefion Dorothea, Walter, Carolin, Ballast, Annika, Holdhof, Dörthe, Göbel, Carolin, Neyazi, Sina, Varghese, Julian, Albert, Thomas Karl, Kerl, Kornelius, Schüller, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322855/
https://www.ncbi.nlm.nih.gov/pubmed/37407554
http://dx.doi.org/10.1038/s41389-023-00481-3

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