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Molecular mechanism of ensitrelvir inhibiting SARS-CoV-2 main protease and its variants
SARS-CoV-2 poses an unprecedented threat to the world as the causative agent of the COVID-19 pandemic. Among a handful of therapeutics developed for the prevention and treatment of SARS-CoV-2 infection, ensitrelvir is the first noncovalent and nonpeptide oral inhibitor targeting the main protease (M...
Autores principales: | Lin, Mengmeng, Zeng, Xudong, Duan, Yinkai, Yang, Zinan, Ma, Yuanyuan, Yang, Haitao, Yang, Xiuna, Liu, Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322880/ https://www.ncbi.nlm.nih.gov/pubmed/37407698 http://dx.doi.org/10.1038/s42003-023-05071-y |
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