RNA m(6)A-Regulated circ-ZNF609 Suppression Ameliorates Doxorubicin-Induced Cardiotoxicity by Upregulating FTO

Cardiac death is a major burden for cancer survivors, yet there is currently no effective treatment for doxorubicin (DOX)-induced cardiotoxicity. Here, we report that circ-ZNF609 knockdown knockdown had cardioprotective effects against DOX-induced cardiomyocyte toxicity. Mechanistically, circ-ZNF609...

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Detalles Bibliográficos
Autores principales: Yu, Pujiao, Wang, Jiaqi, Xu, Gui-e, Zhao, Xuan, Cui, Xinxin, Feng, Jingyi, Sun, Jiangpeng, Wang, Tianhui, Spanos, Michail, Lehmann, Helge Immo, Li, Guoping, Xu, Jiahong, Wang, Lijun, Xiao, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research - Preclinical
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322883/
https://www.ncbi.nlm.nih.gov/pubmed/37426524
http://dx.doi.org/10.1016/j.jacbts.2022.12.005

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