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Blood transcriptomic signatures associated with molecular changes in the brain and clinical outcomes in Parkinson’s disease

The ability to use blood to predict the outcomes of Parkinson’s disease, including disease progression and cognitive and motor complications, would be of significant clinical value. We undertook bulk RNA sequencing from the caudate and putamen of postmortem Parkinson’s disease (n = 35) and control (...

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Detalles Bibliográficos
Autores principales: Irmady, Krithi, Hale, Caryn R., Qadri, Rizwana, Fak, John, Simelane, Sitsandziwe, Carroll, Thomas, Przedborski, Serge, Darnell, Robert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322907/
https://www.ncbi.nlm.nih.gov/pubmed/37407548
http://dx.doi.org/10.1038/s41467-023-39652-6

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