PDGF-AB Reduces Myofibroblast Differentiation Without Increasing Proliferation After Myocardial Infarction

After myocardial infarction (MI), fibroblasts progress from proliferative to myofibroblast states, resulting in fibrosis. Platelet-derived growth factors (PDGFs) are reported to induce fibroblast proliferation, myofibroblast differentiation, and fibrosis. However, we have previously shown that PDGFs...

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Detalles Bibliográficos
Autores principales: Hume, Robert D., Deshmukh, Tejas, Doan, Tram, Shim, Woo Jun, Kanagalingam, Shaan, Tallapragada, Vikram, Rashid, Fairooj, Marcuello, Maria, Blessing, Daniel, Selvakumar, Dinesh, Raguram, Kalyan, Pathan, Faraz, Graham, Dinny, Ounzain, Samir, Kizana, Eddy, Harvey, Richard P., Palpant, Nathan J., Chong, James J.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research - Preclinical
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322908/
https://www.ncbi.nlm.nih.gov/pubmed/37426530
http://dx.doi.org/10.1016/j.jacbts.2022.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322908/
https://www.ncbi.nlm.nih.gov/pubmed/37426530
http://dx.doi.org/10.1016/j.jacbts.2022.11.006

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