Cargando…

PDGF-AB Reduces Myofibroblast Differentiation Without Increasing Proliferation After Myocardial Infarction

After myocardial infarction (MI), fibroblasts progress from proliferative to myofibroblast states, resulting in fibrosis. Platelet-derived growth factors (PDGFs) are reported to induce fibroblast proliferation, myofibroblast differentiation, and fibrosis. However, we have previously shown that PDGFs...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hume, Robert D., Deshmukh, Tejas, Doan, Tram, Shim, Woo Jun, Kanagalingam, Shaan, Tallapragada, Vikram, Rashid, Fairooj, Marcuello, Maria, Blessing, Daniel, Selvakumar, Dinesh, Raguram, Kalyan, Pathan, Faraz, Graham, Dinny, Ounzain, Samir, Kizana, Eddy, Harvey, Richard P., Palpant, Nathan J., Chong, James J.H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Research - Preclinical
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322908/ https://www.ncbi.nlm.nih.gov/pubmed/37426530 http://dx.doi.org/10.1016/j.jacbts.2022.11.006

Ejemplares similares

Tropoelastin Improves Post-Infarct Cardiac Function
por: Hume, Robert D., et al.
Publicado: (2022)

The PDGF pathway in breast cancer is linked to tumour aggressiveness, triple-negative subtype and early recurrence
por: Jansson, Sara, et al.
Publicado: (2018)

Cardiac Mesenchymal Stem Cells Promote Fibrosis and Remodeling in Heart Failure: Role of PDGF Signaling
por: Hamid, Tariq, et al.
Publicado: (2022)

Cardiomyocyte Lineage Specification in Adult Human Cardiac Precursor Cells Via Modulation of Enhancer-Associated Long Noncoding RNA Expression
por: Plaisance, Isabelle, et al.
Publicado: (2016)

PDGF-Rα gene expression predicts proliferation, but PDGF-A suppresses transdifferentiation of neonatal mouse lung myofibroblasts
por: Kimani, Patricia W, et al.
Publicado: (2009)

Comparative assessment of motion averaged free-breathing or breath-held cardiac magnetic resonance imaging protocols in a porcine myocardial infarction model
por: Selvakumar, Dinesh, et al.
Publicado: (2022)

Inhibition of Contractile Function in Human Joint Capsule Myofibroblasts by Targeting the TGF-β1 and PDGF Pathways
por: Mattyasovszky, Stefan G., et al.
Publicado: (2016)

PDGF and PDGF receptors in glioma
por: Nazarenko, Inga, et al.
Publicado: (2012)

PDGF-AA and PDGF-BB biosynthesis: proprotein processing in the Golgi complex and lysosomal degradation of PDGF-BB retained intracellularly
Publicado: (1992)

Myofibroblasts as important diagnostic and prognostic indicators of oral squamous cell carcinoma: An immunohistochemical study in normal oral mucosa, epithelial dysplasia, and oral squamous cell carcinoma
por: Shete, Mrinal V., et al.
Publicado: (2020)

Accumulation of PDGF B and cell-binding forms of PDGF A in the extracellular matrix
Publicado: (1993)

Variations in indexation of left atrial volume across different races
por: Ferkh, Aaisha, et al.
Publicado: (2023)

Central carbon metabolism in the progression of mammary carcinoma
por: Richardson, Adam D., et al.
Publicado: (2007)

The spectrum of ATM missense variants and their contribution to contralateral breast cancer
por: Broeks, Annegien, et al.
Publicado: (2007)

Stromal mast cells in invasive breast cancer are a marker of favourable prognosis: a study of 4,444 cases
por: Rajput, Ashish B., et al.
Publicado: (2007)

Loss of expression of FANCD2 protein in sporadic and hereditary breast cancer
por: van der Groep, Petra, et al.
Publicado: (2007)

Preclinical activity of gefitinib in non-keratinizing nasopharyngeal carcinoma cell lines and biomarkers of response
por: Ma, Brigette B.Y., et al.
Publicado: (2009)

Paclitaxel in self-micro emulsifying formulations: oral bioavailability study in mice
por: Oostendorp, Roos L., et al.
Publicado: (2010)

Pankiller effect of prolonged exposure to menadione on glioma cells: potentiation by vitamin C
por: Vita, Marina F., et al.
Publicado: (2010)

Long-term blinded placebo-controlled study of SNT-MC17/idebenone in the dystrophin deficient mdx mouse: cardiac protection and improved exercise performance
por: Buyse, Gunnar M., et al.
Publicado: (2009)

Development and characterization of CD22-targeted pegylated-liposomal doxorubicin (IL-PLD)
por: O’Donnell, Robert T., et al.
Publicado: (2009)

Acute atrial tachyarrhythmia induces angiotensin II type 1 receptor-mediated oxidative stress and microvascular flow abnormalities in the ventricles
por: Goette, Andreas, et al.
Publicado: (2009)

CD36-mediated activation of endothelial cell apoptosis by an N-terminal recombinant fragment of thrombospondin-2 inhibits breast cancer growth and metastasis in vivo
por: Koch, Manuel, et al.
Publicado: (2010)

Genomic analysis identifies unique signatures predictive of brain, lung, and liver relapse
por: Harrell, J. Chuck, et al.
Publicado: (2011)

Role of ghrelin in food reward: impact of ghrelin on sucrose self-administration and mesolimbic dopamine and acetylcholine receptor gene expression
por: Skibicka, Karolina P, et al.
Publicado: (2012)

Growth inhibition induced by antiprogestins RU-38486, ORG-31710, and CDB-2914 in ovarian cancer cells involves inhibition of cyclin dependent kinase 2
por: Goyeneche, Alicia A., et al.
Publicado: (2011)

Glutamatergic regulation of ghrelin-induced activation of the mesolimbic dopamine system
por: Jerlhag, Elisabet, et al.
Publicado: (2011)

Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models
por: Bergman, Andries M., et al.
Publicado: (2010)

Genome-Wide Association Studies (GWAS) breast cancer susceptibility loci in Arabs: susceptibility and prognostic implications in Tunisians
por: Shan, Jingxuan, et al.
Publicado: (2012)

Expression of the BRCA1 complex member BRE predicts disease free survival in breast cancer
por: Noordermeer, Sylvie M., et al.
Publicado: (2012)

Oncogene amplification in male breast cancer: analysis by multiplex ligation-dependent probe amplification
por: Kornegoor, Robert, et al.
Publicado: (2012)

Germline copy number variants are not associated with globally acquired copy number changes in familial breast tumours
por: Walker, Logan C., et al.
Publicado: (2012)

Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer
por: Wang, Neng, et al.
Publicado: (2012)

MUTYH gene variants and breast cancer in a Dutch case–control study
por: Out, Astrid A., et al.
Publicado: (2012)

Inactivation of GPR30 reduces growth of triple-negative breast cancer cells: possible application in targeted therapy
por: Girgert, Rainer, et al.
Publicado: (2012)

Overexpression of a novel cell cycle regulator ecdysoneless in breast cancer: a marker of poor prognosis in HER2/neu-overexpressing breast cancer patients
por: Zhao, Xiangshan, et al.
Publicado: (2012)

Assessing HER2 amplification in breast cancer: findings from the Australian In Situ Hybridization Program
por: Bilous, Michael, et al.
Publicado: (2012)

Therapeutic potential for phenytoin: targeting Na(v)1.5 sodium channels to reduce migration and invasion in metastatic breast cancer
por: Yang, Ming, et al.
Publicado: (2012)

Caffeic Acid Phenethyl Ester (CAPE) derived from propolis, a honeybee product, inhibits growth of breast cancer stem cells
por: Omene, Coral O., et al.
Publicado: (2011)

Metabolism and accumulation of the lipophilic deoxynucleoside analogs elacytarabine and CP-4126
por: Adema, Auke D., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_pf3a4e1lccr4kpab98dgus12tu