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Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies

Hepatitis C virus (HCV) is a major global health burden as the leading causative agent of chronic liver disease and hepatocellular carcinoma. While the main antigenic target for HCV-neutralizing antibodies is the membrane-associated E1E2 surface glycoprotein, the development of effective vaccines ha...

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Detalles Bibliográficos
Autores principales:	Metcalf, Matthew C., Janus, Benjamin M., Yin, Rui, Wang, Ruixue, Guest, Johnathan D., Pozharski, Edwin, Law, Mansun, Mariuzza, Roy A., Toth, Eric A., Pierce, Brian G., Fuerst, Thomas R., Ofek, Gilad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322937/ https://www.ncbi.nlm.nih.gov/pubmed/37407593 http://dx.doi.org/10.1038/s41467-023-39659-z

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