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Low expression of Ki-67/MIB-1 labeling index in IDH wild type glioblastoma predicts prolonged survival independently by MGMT methylation status

PURPOSE: The Ki-67/MIB-1 labeling index (LI) is clinically used to differentiate between high and low-grade gliomas, while its prognostic value remains questionable. Glioblastoma (GBM) expressing wild-type isocitrate dehydrogenase IDH(wt), a relatively common malignant brain tumor in adults, is char...

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Detalles Bibliográficos
Autores principales: Tini, Paolo, Yavoroska, Mariya, Mazzei, Maria Antonietta, Miracco, Clelia, Pirtoli, Luigi, Tomaciello, Miriam, Marampon, Francesco, Minniti, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322955/
https://www.ncbi.nlm.nih.gov/pubmed/37227648
http://dx.doi.org/10.1007/s11060-023-04342-2