Integrating somatic CNV and gene expression in breast cancers from women with PTEN hamartoma tumor syndrome

Women with germline PTEN variants (PTEN hamartoma tumor syndrome, PHTS) have up to 85% lifetime risk of female breast cancer (BC). We previously showed that PHTS-derived BCs are distinct from sporadic BCs both at the clinical and genomic levels. In this study, we examined somatic copy number variati...

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Detalles Bibliográficos
Autores principales: Brewer, Takae, Yehia, Lamis, Bazeley, Peter, Eng, Charis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322985/
https://www.ncbi.nlm.nih.gov/pubmed/37407629
http://dx.doi.org/10.1038/s41525-023-00361-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322985/
https://www.ncbi.nlm.nih.gov/pubmed/37407629
http://dx.doi.org/10.1038/s41525-023-00361-0

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