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Senescent CD8 (+) T cells acquire NK cell‐like innate functions to promote antitumor immunity

It has been suggested that aging of the immune system (immunosenescence) results in a decline in the acquired immune response, which is associated with an increase in age‐related tumorigenesis. T‐cell senescence plays a critical role in immunosenescence and is involved in the age‐related decline of...

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Detalles Bibliográficos
Autores principales: Kakuda, Toshio, Suzuki, Junpei, Matsuoka, Yuko, Kikugawa, Tadahiko, Saika, Takashi, Yamashita, Masakatsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323091/
https://www.ncbi.nlm.nih.gov/pubmed/37186472
http://dx.doi.org/10.1111/cas.15824