A gain‐of‐function mutation in microRNA 142 is sufficient to cause the development of T‐cell leukemia in mice

MicroRNAs (miRNAs) play a crucial role in regulating gene expression. MicroRNA expression levels fluctuate, and point mutations and methylation occur in cancer cells; however, to date, there have been no reports of carcinogenic point mutations in miRNAs. MicroRNA 142 (miR‐142) is frequently mutated...

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Detalles Bibliográficos
Autores principales: Kawano, Shingo, Araki, Kimi, Bai, Jie, Furukawa, Imari, Tateishi, Keigo, Yoshinobu, Kumiko, Usuki, Shingo, Nimmo, Rachael A., Kaname, Tadashi, Yoshihara, Masaharu, Takahashi, Satoru, Sashida, Goro, Araki, Masatake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323092/
https://www.ncbi.nlm.nih.gov/pubmed/36945113
http://dx.doi.org/10.1111/cas.15794

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