PPARγ inhibited tumor immune escape by inducing PD‐L1 autophagic degradation

Blockade of the programmed death 1 (PD‐1)/ programmed death ligand 1 (PD‐L1) immune checkpoint could increase antitumor immunotherapy for multiple types of cancer, but the response rate of patients is about 10%–40%. Peroxisome proliferator activated receptor γ (PPARγ) plays an important role in regu...

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Detalles Bibliográficos
Autores principales: Gou, Qian, Che, Suning, Chen, Mingjun, Chen, Huiqing, Shi, Juanjuan, Hou, Yongzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323095/
https://www.ncbi.nlm.nih.gov/pubmed/37096255
http://dx.doi.org/10.1111/cas.15818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323095/
https://www.ncbi.nlm.nih.gov/pubmed/37096255
http://dx.doi.org/10.1111/cas.15818

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