Optogenetically engineered Ca(2+) oscillation-mediated DRP1 activation promotes mitochondrial fission and cell death

Mitochondrial dynamics regulate the quality and morphology of mitochondria. Calcium (Ca(2+)) plays an important role in regulating mitochondrial function. Here, we investigated the effects of optogenetically engineered Ca(2+) signaling on mitochondrial dynamics. More specifically, customized illumin...

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Detalles Bibliográficos
Autores principales: Lai, Yi-Shyun, Chang, Cheng-Chi, Chen, Yong-Yi, Nguyen, Thi My Hang, Xu, Jixuan, Chen, Ying-Chi, Chang, Yu-Fen, Wang, Chia-Yih, Chen, Pai-Sheng, Lin, Shih-Chieh, Peng, I-Chen, Tsai, Shaw-Jenq, Chiu, Wen-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323238/
https://www.ncbi.nlm.nih.gov/pubmed/37232206
http://dx.doi.org/10.1242/jcs.260819

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