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Computer-aided drug design approaches applied to screen natural product’s structural analogs targeting arginase in Leishmania spp

Introduction: Leishmaniasis is a disease with high mortality rates and approximately 1.5 million new cases each year. Despite the new approaches and advances to fight the disease, there are no effective therapies. Methods: Hence, this study aims to screen for natural products' structural analog...

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Detalles Bibliográficos
Autores principales: Barazorda-Ccahuana, Haruna Luz, Goyzueta-Mamani, Luis Daniel, Candia Puma, Mayron Antonio, Simões de Freitas, Camila, de Sousa Vieria Tavares, Grasiele, Pagliara Lage, Daniela, Ferraz Coelho, Eduardo Antonio, Chávez-Fumagalli, Miguel Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323282/
https://www.ncbi.nlm.nih.gov/pubmed/37424744
http://dx.doi.org/10.12688/f1000research.129943.3