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METTL3 Affects Spinal Cord Neuronal Apoptosis by Regulating Bcl-2 m6A Modifications After Spinal Cord Injury

OBJECTIVE: Spinal cord injury (SCI) is a severe type of neurological trauma. N6-methyladenosine (m6A) modification is one of the most common internal modifications of RNA. The role of METTL3, the predominant methylation enzyme of m6A modification, in SCI remains unclear. This study aimed to investig...

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Detalles Bibliográficos
Autores principales: Guo, Shengyu, Lin, Taotao, Chen, Gang, Shangguan, Zhitao, Zhou, Linquan, Chen, Zhi, Shi, Tengbin, Chen, Dehui, Wang, Zhenyu, Liu, Wenge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Spinal Neurosurgery Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323356/
https://www.ncbi.nlm.nih.gov/pubmed/37401082
http://dx.doi.org/10.14245/ns.2346170.085