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Long‐Chain Acyl Carnitines Aggravate Polystyrene Nanoplastics‐Induced Atherosclerosis by Upregulating MARCO (Adv. Sci. 19/2023)

Microplastics and Nanoplastics Qin Qiong is revered as a venerable guardian deity in ancient Chinese mythology. Similarly, macrophages serve as its protectors within the cardiovascular system. In article number 2205876, Yizhou Zhong, Zhenlie Huang, and co‐workers unveil that when the cardiovascular...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Liang, Boxuan, Huang, Yuji, Li, Zhiming, Zhang, Bingli, Du, Jiaxin, Ye, Rongyi, Xian, Hongyi, Deng, Yanhong, Xiu, Jiancheng, Yang, Xingfen, Ichihara, Sahoko, Ichihara, Gaku, Zhong, Yizhou, Huang, Zhenlie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323644/
http://dx.doi.org/10.1002/advs.202370121
Descripción
Sumario:Microplastics and Nanoplastics Qin Qiong is revered as a venerable guardian deity in ancient Chinese mythology. Similarly, macrophages serve as its protectors within the cardiovascular system. In article number 2205876, Yizhou Zhong, Zhenlie Huang, and co‐workers unveil that when the cardiovascular system is exposed to micro‐ and nanoplastics (MNPs), macrophages face not only the direct assault from the MNPs but also simultaneous aggression from long‐chain acylcarnitines, a kind of endogenous chemical compound. These findings have the potential to aid in managing the escalating health risks imposed on humanity by increasing MNP exposure. [Image: see text]