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Mechanical effect of reconstructed shapes of autologous ossicles on middle ear acoustic transmission

Conductive hearing loss is caused by a variety of defects, such as chronic otitis media, osteosclerosis, and malformation of the ossicles. In such cases, the defective bones of the middle ear are often surgically reconstructed using artificial ossicles to increase the hearing ability. However, in so...

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Autores principales: Asakura, Takumi, Ito, Ryuya, Hirabayashi, Motoki, Kurihara, Sho, Kurashina, Yuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323686/
https://www.ncbi.nlm.nih.gov/pubmed/37425366
http://dx.doi.org/10.3389/fbioe.2023.1204972
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author Asakura, Takumi
Ito, Ryuya
Hirabayashi, Motoki
Kurihara, Sho
Kurashina, Yuta
author_facet Asakura, Takumi
Ito, Ryuya
Hirabayashi, Motoki
Kurihara, Sho
Kurashina, Yuta
author_sort Asakura, Takumi
collection PubMed
description Conductive hearing loss is caused by a variety of defects, such as chronic otitis media, osteosclerosis, and malformation of the ossicles. In such cases, the defective bones of the middle ear are often surgically reconstructed using artificial ossicles to increase the hearing ability. However, in some cases, the surgical procedure does not result in increased hearing, especially in a difficult case, for example, when only the footplate of the stapes remains and all of the other bones are destroyed. Herein, the appropriate shapes of the reconstructed autologous ossicles, which are suitable for various types of middle-ear defects, can be determined by adopting an updating calculation based on a method that combines numerical prediction of the vibroacoustic transmission and optimization. In this study, the vibroacoustic transmission characteristics were calculated for bone models of the human middle ear by using the finite element method (FEM), after which Bayesian optimization (BO) was applied. The effect of the shape of artificial autologous ossicles on the acoustic transmission characteristics of the middle ear was investigated with the combined FEM and BO method. The results suggested that the volume of the artificial autologous ossicles especially has a great influence on the numerically obtained hearing levels.
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spelling pubmed-103236862023-07-07 Mechanical effect of reconstructed shapes of autologous ossicles on middle ear acoustic transmission Asakura, Takumi Ito, Ryuya Hirabayashi, Motoki Kurihara, Sho Kurashina, Yuta Front Bioeng Biotechnol Bioengineering and Biotechnology Conductive hearing loss is caused by a variety of defects, such as chronic otitis media, osteosclerosis, and malformation of the ossicles. In such cases, the defective bones of the middle ear are often surgically reconstructed using artificial ossicles to increase the hearing ability. However, in some cases, the surgical procedure does not result in increased hearing, especially in a difficult case, for example, when only the footplate of the stapes remains and all of the other bones are destroyed. Herein, the appropriate shapes of the reconstructed autologous ossicles, which are suitable for various types of middle-ear defects, can be determined by adopting an updating calculation based on a method that combines numerical prediction of the vibroacoustic transmission and optimization. In this study, the vibroacoustic transmission characteristics were calculated for bone models of the human middle ear by using the finite element method (FEM), after which Bayesian optimization (BO) was applied. The effect of the shape of artificial autologous ossicles on the acoustic transmission characteristics of the middle ear was investigated with the combined FEM and BO method. The results suggested that the volume of the artificial autologous ossicles especially has a great influence on the numerically obtained hearing levels. Frontiers Media S.A. 2023-06-22 /pmc/articles/PMC10323686/ /pubmed/37425366 http://dx.doi.org/10.3389/fbioe.2023.1204972 Text en Copyright © 2023 Asakura, Ito, Hirabayashi, Kurihara and Kurashina. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Asakura, Takumi
Ito, Ryuya
Hirabayashi, Motoki
Kurihara, Sho
Kurashina, Yuta
Mechanical effect of reconstructed shapes of autologous ossicles on middle ear acoustic transmission
title Mechanical effect of reconstructed shapes of autologous ossicles on middle ear acoustic transmission
title_full Mechanical effect of reconstructed shapes of autologous ossicles on middle ear acoustic transmission
title_fullStr Mechanical effect of reconstructed shapes of autologous ossicles on middle ear acoustic transmission
title_full_unstemmed Mechanical effect of reconstructed shapes of autologous ossicles on middle ear acoustic transmission
title_short Mechanical effect of reconstructed shapes of autologous ossicles on middle ear acoustic transmission
title_sort mechanical effect of reconstructed shapes of autologous ossicles on middle ear acoustic transmission
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323686/
https://www.ncbi.nlm.nih.gov/pubmed/37425366
http://dx.doi.org/10.3389/fbioe.2023.1204972
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