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Composite aortic root replacement in African patients with type A aortic dissection: report of 12 cases

Type A aortic dissection (TAAD) is associated with high mortality in the absence of appropriate surgical therapy. The involvement of the aortic root by the intimal tear and the presence of severe aortic insufficiency will require a more radical approach with composite root replacement (CRR) in most...

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Autores principales: Mvondo, Charles Mve, Yon, Laurence Carole Ngo, Kengni, Hermann Nestor Tsague, Ngowe, Marcelin Ngowe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323817/
https://www.ncbi.nlm.nih.gov/pubmed/37426463
http://dx.doi.org/10.11604/pamj.2023.45.18.37147
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author Mvondo, Charles Mve
Yon, Laurence Carole Ngo
Kengni, Hermann Nestor Tsague
Ngowe, Marcelin Ngowe
author_facet Mvondo, Charles Mve
Yon, Laurence Carole Ngo
Kengni, Hermann Nestor Tsague
Ngowe, Marcelin Ngowe
author_sort Mvondo, Charles Mve
collection PubMed
description Type A aortic dissection (TAAD) is associated with high mortality in the absence of appropriate surgical therapy. The involvement of the aortic root by the intimal tear and the presence of severe aortic insufficiency will require a more radical approach with composite root replacement (CRR) in most of the patients. We briefly report our surgical experience following CRR in 12 patients presenting with TAAD in our department. Between November 2009 and January 2022, a total of twelve (n=12) patients diagnosed with TAAD were operated in our institution. Clinical data and surgical outcomes were retrospectively reviewed. The mean age at admission was 51.1 ± 12.43 years (range: 34-72). One patient met the criteria for Marfan´s disease (1/12, 8.3%). The operative mortality was 16.66% (2/12). Composite root replacement with a mechanical valved conduit was performed in the majority (11/12, 91.66%;) whereas a separated supracoronary graft replacement and aortic valve replacement were performed in one patient. Concomitant aortic arch surgery (hemi or total) was done in 9/12 patients (75%). The commonest postoperative complications were: chest re-exploration for bleeding in 2/12 (16.66%), transitory cerebral ischemia in 1/12 (8.33%) and low cardiac output syndrome in 2/12 (16.66%). The mean length of stay in the Intensive Care Unit (ICU) was 4.8±3.8 days (range: 2-17). Delayed referral of patients with TAAD was observed in the majority of patients as they were operated in the subacute or chronic phase. Composite root replacement in these patients is associated with acceptable outcomes despite complex anatomic-pathological lesions.
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spelling pubmed-103238172023-07-07 Composite aortic root replacement in African patients with type A aortic dissection: report of 12 cases Mvondo, Charles Mve Yon, Laurence Carole Ngo Kengni, Hermann Nestor Tsague Ngowe, Marcelin Ngowe Pan Afr Med J Case Series Type A aortic dissection (TAAD) is associated with high mortality in the absence of appropriate surgical therapy. The involvement of the aortic root by the intimal tear and the presence of severe aortic insufficiency will require a more radical approach with composite root replacement (CRR) in most of the patients. We briefly report our surgical experience following CRR in 12 patients presenting with TAAD in our department. Between November 2009 and January 2022, a total of twelve (n=12) patients diagnosed with TAAD were operated in our institution. Clinical data and surgical outcomes were retrospectively reviewed. The mean age at admission was 51.1 ± 12.43 years (range: 34-72). One patient met the criteria for Marfan´s disease (1/12, 8.3%). The operative mortality was 16.66% (2/12). Composite root replacement with a mechanical valved conduit was performed in the majority (11/12, 91.66%;) whereas a separated supracoronary graft replacement and aortic valve replacement were performed in one patient. Concomitant aortic arch surgery (hemi or total) was done in 9/12 patients (75%). The commonest postoperative complications were: chest re-exploration for bleeding in 2/12 (16.66%), transitory cerebral ischemia in 1/12 (8.33%) and low cardiac output syndrome in 2/12 (16.66%). The mean length of stay in the Intensive Care Unit (ICU) was 4.8±3.8 days (range: 2-17). Delayed referral of patients with TAAD was observed in the majority of patients as they were operated in the subacute or chronic phase. Composite root replacement in these patients is associated with acceptable outcomes despite complex anatomic-pathological lesions. The African Field Epidemiology Network 2023-05-05 /pmc/articles/PMC10323817/ /pubmed/37426463 http://dx.doi.org/10.11604/pamj.2023.45.18.37147 Text en Copyright: Charles Mve Mvondo et al. https://creativecommons.org/licenses/by/4.0/The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Series
Mvondo, Charles Mve
Yon, Laurence Carole Ngo
Kengni, Hermann Nestor Tsague
Ngowe, Marcelin Ngowe
Composite aortic root replacement in African patients with type A aortic dissection: report of 12 cases
title Composite aortic root replacement in African patients with type A aortic dissection: report of 12 cases
title_full Composite aortic root replacement in African patients with type A aortic dissection: report of 12 cases
title_fullStr Composite aortic root replacement in African patients with type A aortic dissection: report of 12 cases
title_full_unstemmed Composite aortic root replacement in African patients with type A aortic dissection: report of 12 cases
title_short Composite aortic root replacement in African patients with type A aortic dissection: report of 12 cases
title_sort composite aortic root replacement in african patients with type a aortic dissection: report of 12 cases
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323817/
https://www.ncbi.nlm.nih.gov/pubmed/37426463
http://dx.doi.org/10.11604/pamj.2023.45.18.37147
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