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Microsatellite instability in noncolorectal and nonendometrial malignancies in patients with Lynch syndrome

BACKGROUND: Individuals with Lynch syndrome are at increased hereditary risk of colorectal and endometrial carcinomas with microsatellite instability (MSI-H) and mismatch repair-deficiency (dMMR), which make these tumors vulnerable to therapy with immune checkpoint inhibitors. Our aim is to assess h...

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Detalles Bibliográficos
Autores principales:	Elze, Lisa, van der Post, Rachel S, Vos, Janet R, Mensenkamp, Arjen R, de Hullu, Mirjam S C, Nagtegaal, Iris D, Hoogerbrugge, Nicoline, de Voer, Richarda M, Ligtenberg, Marjolijn J L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323896/ https://www.ncbi.nlm.nih.gov/pubmed/37018159 http://dx.doi.org/10.1093/jnci/djad063

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