NUAK1 governs centrosome replication in pancreatic cancer via MYPT1/PP1β and GSK3β‐dependent regulation of PLK4

The AMP‐activated protein kinase (AMPK)‐related kinase NUAK1 (NUAK family SNF1‐like kinase 1) has emerged as a potential vulnerability in MYC‐dependent cancer but the biological roles of NUAK1 in different settings are poorly characterised, and the spectrum of cancer types that exhibit a requirement...

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Detalles Bibliográficos
Autores principales: Whyte, Declan, Skalka, George, Walsh, Peter, Wilczynska, Ania, Paul, Nikki R., Mitchell, Claire, Nixon, Colin, Clarke, William, Bushell, Martin, Morton, Jennifer P., Murphy, Daniel J., Muthalagu, Nathiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323901/
https://www.ncbi.nlm.nih.gov/pubmed/36975767
http://dx.doi.org/10.1002/1878-0261.13425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323901/
https://www.ncbi.nlm.nih.gov/pubmed/36975767
http://dx.doi.org/10.1002/1878-0261.13425

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