Safety and Immunogenicity of Radiation-Attenuated PfSPZ Vaccine in Equatoguinean Infants, Children, and Adults

The radiation-attenuated Plasmodium falciparum sporozoites (PfSPZ) Vaccine has demonstrated safety and immunogenicity in 5-month-old to 50-year-old Africans in multiple trials. Except for one, each trial has restricted enrollment to either infants and children or adults < 50 years old. This trial...

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Detalles Bibliográficos
Autores principales: Jongo, Said A., Urbano Nsue Ndong Nchama, Vicente, Church, L. W. Preston, Olotu, Ally, Manock, Stephen R., Schindler, Tobias, Mtoro, Ali, KC, Natasha, Devinsky, Orrin, Zan, Elcin, Hamad, Ali, Nyakarungu, Elizabeth, Mpina, Maxmillian, Deal, Anna, Bijeri, José Raso, Ondo Mangue, Martin Eka, Ntutumu Pasialo, Beltrán Ekua, Nguema, Genaro Nsue, Rivas, Matilde Riloha, Chemba, Mwajuma, Ramadhani, Kamaka K., James, Eric R., Stabler, Thomas C., Abebe, Yonas, Riyahi, Pouria, Saverino, Elizabeth S., Sax, Julian, Hosch, Salome, Tumbo, Anneth, Gondwe, Linda, Segura, J. Luis, Falla, Carlos Cortes, Phiri, Wonder Philip, Hergott, Dianna E. B., García, Guillermo A., Maas, Carl, Murshedkar, Tooba, Billingsley, Peter F., Tanner, Marcel, Ayekaba, Mitoha Ondo’o, Sim, B. Kim Lee, Daubenberger, Claudia, Richie, Thomas L., Abdulla, Salim, Hoffman, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324022/
https://www.ncbi.nlm.nih.gov/pubmed/37160281
http://dx.doi.org/10.4269/ajtmh.22-0773

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