Molecular Representations in Machine-Learning-Based Prediction of PK Parameters for Insulin Analogs

[Image: see text] Therapeutic peptides and proteins derived from either endogenous hormones, such as insulin, or de novo design via display technologies occupy a distinct pharmaceutical space in between small molecules and large proteins such as antibodies. Optimizing the pharmacokinetic (PK) profil...

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Detalles Bibliográficos
Autores principales: Einarson, Kasper A., Bendtsen, Kristian M., Li, Kang, Thomsen, Maria, Kristensen, Niels R., Winther, Ole, Fulle, Simone, Clemmensen, Line, Refsgaard, Hanne H.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324072/
https://www.ncbi.nlm.nih.gov/pubmed/37426277
http://dx.doi.org/10.1021/acsomega.3c01218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324072/
https://www.ncbi.nlm.nih.gov/pubmed/37426277
http://dx.doi.org/10.1021/acsomega.3c01218

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