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Molecular Representations in Machine-Learning-Based Prediction of PK Parameters for Insulin Analogs
[Image: see text] Therapeutic peptides and proteins derived from either endogenous hormones, such as insulin, or de novo design via display technologies occupy a distinct pharmaceutical space in between small molecules and large proteins such as antibodies. Optimizing the pharmacokinetic (PK) profil...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324072/ https://www.ncbi.nlm.nih.gov/pubmed/37426277 http://dx.doi.org/10.1021/acsomega.3c01218 |