Targeting GBM with an Oncolytic Picornavirus SVV-001 alone and in combination with fractionated Radiation in a Novel Panel of Orthotopic PDX models

BACKGROUND: Animal models representing different molecular subtypes of glioblastoma multiforme (GBM) is desired for developing new therapies. SVV-001 is an oncolytic virus selectively targeting cancer cells. It’s capacity of passing through the blood brain barrier makes is an attractive novel approa...

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Detalles Bibliográficos
Autores principales: Zhang, Huiyuan, Du, Yuchen, Qi, Lin, Xiao, Sophie, Braun, Frank K., Kogiso, Mari, Huang, Yulun, Huang, Frank, Abdallah, Aalaa, Suarez, Milagros, Karthick, Sekar, Ahmed, Nabil M., Salsman, Vita S., Baxter, Patricia A., Su, Jack M., Brat, Daniel J., Hellenbeck, Paul L., Teo, Wan-Yee, Patel, Akash J., Li, Xiao-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324131/
https://www.ncbi.nlm.nih.gov/pubmed/37415222
http://dx.doi.org/10.1186/s12967-023-04237-w

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