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A study of the interaction space of two lactate dehydrogenase isoforms (LDHA and LDHB) and some of their inhibitors using proteochemometrics modeling
Lactate dehydrogenase (LDH) is a tetramer enzyme that converts pyruvate to lactate reversibly. This enzyme becomes important because it is associated with diseases such as cancers, heart disease, liver problems, and most importantly, corona disease. As a system-based method, proteochemometrics does...
Autores principales: | Damavandi, Sedigheh, Shiri, Fereshteh, Emamjomeh, Abbasali, Pirhadi, Somayeh, Beyzaei, Hamid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324138/ https://www.ncbi.nlm.nih.gov/pubmed/37415191 http://dx.doi.org/10.1186/s13065-023-00991-6 |
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