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Cancer-associated fibroblast-derived PAI-1 promotes lymphatic metastasis via the induction of EndoMT in lymphatic endothelial cells

BACKGROUND: Endothelial-mesenchymal transition (EndoMT) is an emerging adaptive process that modulates lymphatic endothelial function to drive aberrant lymphatic vascularization in the tumour microenvironment (TME); however, the molecular determinants that govern the functional role of EndoMT remain...

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Detalles Bibliográficos
Autores principales: Wei, Wen-Fei, Zhou, Hui-Ling, Chen, Pei-Yu, Huang, Xiao-Lan, Huang, Long, Liang, Luo-Jiao, Guo, Chu-Hong, Zhou, Chen-Fei, Yu, Lan, Fan, Liang-Sheng, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324144/
https://www.ncbi.nlm.nih.gov/pubmed/37415190
http://dx.doi.org/10.1186/s13046-023-02714-0

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