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Aberrant KAT2A accumulations render TRIM22-low melanoma sensitive to Notch1 inhibitors via epigenetic reprogramming

BACKGROUND: Aberrant ubiquitin-proteasome system (UPS) triggers various disorders of biological events and contributes to progression of tumorigenesis. The tripartite motif containing 22 (TRIM22) was demonstrated to participate in the progression of multiple malignancies. Nevertheless, the role of T...

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Detalles Bibliográficos
Autores principales:	Gu, Xiaoli, Min, Wei, Zeng, Yibin, Fan, Ni, Qian, Qihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324160/ https://www.ncbi.nlm.nih.gov/pubmed/37415153 http://dx.doi.org/10.1186/s12967-023-04305-1

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