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Notoginsenoside R1 can inhibit the interaction between FGF1 and VEGFA to retard podocyte apoptosis

BACKGROUND: Diabetic nephropathy (DN) is a chronic condition resulting from microangiopathy in a high-glucose environment. The evaluation of vascular injury in DN has primarily focused on active molecules of VEGF, namely VEGFA and VEGF2(F2R). Notoginsenoside R1 (NGR1), a traditional anti-inflammator...

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Detalles Bibliográficos
Autores principales: Li, ChangYan, Zhong, HuaChen, Ma, JingYuan, Liang, Zhang, Zhang, Le, Liu, Tao, Fan, WenXing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324173/
https://www.ncbi.nlm.nih.gov/pubmed/37415174
http://dx.doi.org/10.1186/s12902-023-01402-6

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