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Histone acetyltransferase P300 deficiency promotes ferroptosis of vascular smooth muscle cells by activating the HIF-1α/HMOX1 axis

BACKGROUND: E1A-associated 300-kDa protein (P300), an endogenous histone acetyltransferase, contributes to modifications of the chromatin landscape of genes involved in multiple cardiovascular diseases. Ferroptosis of vascular smooth muscle cells (VSMCs) is a novel pathological mechanism of aortic d...

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Detalles Bibliográficos
Autores principales:	Shi, Juan, Wang, Qun-Hui, Wei, Xiang, Huo, Bo, Ye, Jian-Nan, Yi, Xin, Feng, Xin, Fang, Ze-Min, Jiang, Ding-Sheng, Ma, Ming-Jia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324182/ https://www.ncbi.nlm.nih.gov/pubmed/37415103 http://dx.doi.org/10.1186/s10020-023-00694-7

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