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Report of a phase 1 clinical trial for safety assessment of human placental mesenchymal stem cells therapy in patients with critical limb ischemia (CLI)
BACKGROUND: Critical limb ischemia (CLI) is associated with increased risk of tissue loss, leading to significant morbidity and mortality. Therapeutic angiogenesis using cell-based treatments, notably mesenchymal stem cells (MSCs), is essential for enhancing blood flow to ischemic areas in subjects...
Autores principales: | Shirbaghaee, Zeinab, Heidari Keshel, Saeed, Rasouli, Mehdi, Valizadeh, Majid, Hashemi Nazari, Seyed Saeed, Hassani, Mohammad, Soleimani, Masoud |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324209/ https://www.ncbi.nlm.nih.gov/pubmed/37408043 http://dx.doi.org/10.1186/s13287-023-03390-9 |
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