Cargando…

Association of dietary intake and cervical cancer: a prevention strategy

INTRODUCTION: Cervical cancer is one of lethal cancers in women. As a global concern, identifying important factors of cancer is a useful strategy for prevention. Due to the role of diet/nutrition factors for cancer, the purpose of our study was to determine the impact of 150 nutrition/vitamin facto...

Descripción completa

Detalles Bibliográficos
Autores principales: Nazari, Elham, Hasanzadeh, Malihe, Rezvani, Reza, Rejali, Marzieh, Badpeyma, Mohaddeseh, Delaram, Zeinab, Mousavi-Seresht, Leila, Akbari, Mahdieh, Khazaei, Majid, Ferns, Gordon A., Avan, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324228/
https://www.ncbi.nlm.nih.gov/pubmed/37415218
http://dx.doi.org/10.1186/s13027-023-00517-8
_version_ 1785069106175672320
author Nazari, Elham
Hasanzadeh, Malihe
Rezvani, Reza
Rejali, Marzieh
Badpeyma, Mohaddeseh
Delaram, Zeinab
Mousavi-Seresht, Leila
Akbari, Mahdieh
Khazaei, Majid
Ferns, Gordon A.
Avan, Amir
author_facet Nazari, Elham
Hasanzadeh, Malihe
Rezvani, Reza
Rejali, Marzieh
Badpeyma, Mohaddeseh
Delaram, Zeinab
Mousavi-Seresht, Leila
Akbari, Mahdieh
Khazaei, Majid
Ferns, Gordon A.
Avan, Amir
author_sort Nazari, Elham
collection PubMed
description INTRODUCTION: Cervical cancer is one of lethal cancers in women. As a global concern, identifying important factors of cancer is a useful strategy for prevention. Due to the role of diet/nutrition factors for cancer, the purpose of our study was to determine the impact of 150 nutrition/vitamin factors and 50 non-nutritional factor in cervical cancer and phase. METHODS: Population samples of 2088 healthy subjects and patients with cervical cancer were investigated. 200 factors such as vitamin E, B1, B6, fruits, HPV, and age were gathered. Deep learning, Decision tree, and correlation matrix were used for modeling and identifying important factors. SPSS 26, R4.0.3, and Rapid miner were utilized for implementation. RESULTS: Our findings indicated that zinc, Iron, Niacin, Potassium, Phosphorous, and Cooper have a beneficial impact in reducing the risk of cervical cancer and progression of phase in Iranian women, as well as Salt, snacks and milk Were identified as high-risk food factors (P value < 0.05 and coefficient correlation > 0.6). Also, alcohol, and sex patient with two groups, HPV positive have an impact on cervical cancer incidence. Phosphorus and selenium in the Micronutrients category (R(2) = 0.85, AUC = 0.993) and polyunsaturated fatty acid and salt in the Macronutrients category and other categories of nutrients were identified as the most effective factors in cervical cancer using deep learning (R(2) = 0.93, AUC = 0.999). CONCLUSIONS: A diet and rich nutrition can be helpful for the prevention of cervix cancer and may reduce the risk of disease. Additional research is necessary for different countries.
format Online
Article
Text
id pubmed-10324228
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-103242282023-07-07 Association of dietary intake and cervical cancer: a prevention strategy Nazari, Elham Hasanzadeh, Malihe Rezvani, Reza Rejali, Marzieh Badpeyma, Mohaddeseh Delaram, Zeinab Mousavi-Seresht, Leila Akbari, Mahdieh Khazaei, Majid Ferns, Gordon A. Avan, Amir Infect Agent Cancer Research INTRODUCTION: Cervical cancer is one of lethal cancers in women. As a global concern, identifying important factors of cancer is a useful strategy for prevention. Due to the role of diet/nutrition factors for cancer, the purpose of our study was to determine the impact of 150 nutrition/vitamin factors and 50 non-nutritional factor in cervical cancer and phase. METHODS: Population samples of 2088 healthy subjects and patients with cervical cancer were investigated. 200 factors such as vitamin E, B1, B6, fruits, HPV, and age were gathered. Deep learning, Decision tree, and correlation matrix were used for modeling and identifying important factors. SPSS 26, R4.0.3, and Rapid miner were utilized for implementation. RESULTS: Our findings indicated that zinc, Iron, Niacin, Potassium, Phosphorous, and Cooper have a beneficial impact in reducing the risk of cervical cancer and progression of phase in Iranian women, as well as Salt, snacks and milk Were identified as high-risk food factors (P value < 0.05 and coefficient correlation > 0.6). Also, alcohol, and sex patient with two groups, HPV positive have an impact on cervical cancer incidence. Phosphorus and selenium in the Micronutrients category (R(2) = 0.85, AUC = 0.993) and polyunsaturated fatty acid and salt in the Macronutrients category and other categories of nutrients were identified as the most effective factors in cervical cancer using deep learning (R(2) = 0.93, AUC = 0.999). CONCLUSIONS: A diet and rich nutrition can be helpful for the prevention of cervix cancer and may reduce the risk of disease. Additional research is necessary for different countries. BioMed Central 2023-07-06 /pmc/articles/PMC10324228/ /pubmed/37415218 http://dx.doi.org/10.1186/s13027-023-00517-8 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Nazari, Elham
Hasanzadeh, Malihe
Rezvani, Reza
Rejali, Marzieh
Badpeyma, Mohaddeseh
Delaram, Zeinab
Mousavi-Seresht, Leila
Akbari, Mahdieh
Khazaei, Majid
Ferns, Gordon A.
Avan, Amir
Association of dietary intake and cervical cancer: a prevention strategy
title Association of dietary intake and cervical cancer: a prevention strategy
title_full Association of dietary intake and cervical cancer: a prevention strategy
title_fullStr Association of dietary intake and cervical cancer: a prevention strategy
title_full_unstemmed Association of dietary intake and cervical cancer: a prevention strategy
title_short Association of dietary intake and cervical cancer: a prevention strategy
title_sort association of dietary intake and cervical cancer: a prevention strategy
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324228/
https://www.ncbi.nlm.nih.gov/pubmed/37415218
http://dx.doi.org/10.1186/s13027-023-00517-8
work_keys_str_mv AT nazarielham associationofdietaryintakeandcervicalcancerapreventionstrategy
AT hasanzadehmalihe associationofdietaryintakeandcervicalcancerapreventionstrategy
AT rezvanireza associationofdietaryintakeandcervicalcancerapreventionstrategy
AT rejalimarzieh associationofdietaryintakeandcervicalcancerapreventionstrategy
AT badpeymamohaddeseh associationofdietaryintakeandcervicalcancerapreventionstrategy
AT delaramzeinab associationofdietaryintakeandcervicalcancerapreventionstrategy
AT mousavisereshtleila associationofdietaryintakeandcervicalcancerapreventionstrategy
AT akbarimahdieh associationofdietaryintakeandcervicalcancerapreventionstrategy
AT khazaeimajid associationofdietaryintakeandcervicalcancerapreventionstrategy
AT fernsgordona associationofdietaryintakeandcervicalcancerapreventionstrategy
AT avanamir associationofdietaryintakeandcervicalcancerapreventionstrategy