Cargando…
Association of dietary intake and cervical cancer: a prevention strategy
INTRODUCTION: Cervical cancer is one of lethal cancers in women. As a global concern, identifying important factors of cancer is a useful strategy for prevention. Due to the role of diet/nutrition factors for cancer, the purpose of our study was to determine the impact of 150 nutrition/vitamin facto...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324228/ https://www.ncbi.nlm.nih.gov/pubmed/37415218 http://dx.doi.org/10.1186/s13027-023-00517-8 |
_version_ | 1785069106175672320 |
---|---|
author | Nazari, Elham Hasanzadeh, Malihe Rezvani, Reza Rejali, Marzieh Badpeyma, Mohaddeseh Delaram, Zeinab Mousavi-Seresht, Leila Akbari, Mahdieh Khazaei, Majid Ferns, Gordon A. Avan, Amir |
author_facet | Nazari, Elham Hasanzadeh, Malihe Rezvani, Reza Rejali, Marzieh Badpeyma, Mohaddeseh Delaram, Zeinab Mousavi-Seresht, Leila Akbari, Mahdieh Khazaei, Majid Ferns, Gordon A. Avan, Amir |
author_sort | Nazari, Elham |
collection | PubMed |
description | INTRODUCTION: Cervical cancer is one of lethal cancers in women. As a global concern, identifying important factors of cancer is a useful strategy for prevention. Due to the role of diet/nutrition factors for cancer, the purpose of our study was to determine the impact of 150 nutrition/vitamin factors and 50 non-nutritional factor in cervical cancer and phase. METHODS: Population samples of 2088 healthy subjects and patients with cervical cancer were investigated. 200 factors such as vitamin E, B1, B6, fruits, HPV, and age were gathered. Deep learning, Decision tree, and correlation matrix were used for modeling and identifying important factors. SPSS 26, R4.0.3, and Rapid miner were utilized for implementation. RESULTS: Our findings indicated that zinc, Iron, Niacin, Potassium, Phosphorous, and Cooper have a beneficial impact in reducing the risk of cervical cancer and progression of phase in Iranian women, as well as Salt, snacks and milk Were identified as high-risk food factors (P value < 0.05 and coefficient correlation > 0.6). Also, alcohol, and sex patient with two groups, HPV positive have an impact on cervical cancer incidence. Phosphorus and selenium in the Micronutrients category (R(2) = 0.85, AUC = 0.993) and polyunsaturated fatty acid and salt in the Macronutrients category and other categories of nutrients were identified as the most effective factors in cervical cancer using deep learning (R(2) = 0.93, AUC = 0.999). CONCLUSIONS: A diet and rich nutrition can be helpful for the prevention of cervix cancer and may reduce the risk of disease. Additional research is necessary for different countries. |
format | Online Article Text |
id | pubmed-10324228 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-103242282023-07-07 Association of dietary intake and cervical cancer: a prevention strategy Nazari, Elham Hasanzadeh, Malihe Rezvani, Reza Rejali, Marzieh Badpeyma, Mohaddeseh Delaram, Zeinab Mousavi-Seresht, Leila Akbari, Mahdieh Khazaei, Majid Ferns, Gordon A. Avan, Amir Infect Agent Cancer Research INTRODUCTION: Cervical cancer is one of lethal cancers in women. As a global concern, identifying important factors of cancer is a useful strategy for prevention. Due to the role of diet/nutrition factors for cancer, the purpose of our study was to determine the impact of 150 nutrition/vitamin factors and 50 non-nutritional factor in cervical cancer and phase. METHODS: Population samples of 2088 healthy subjects and patients with cervical cancer were investigated. 200 factors such as vitamin E, B1, B6, fruits, HPV, and age were gathered. Deep learning, Decision tree, and correlation matrix were used for modeling and identifying important factors. SPSS 26, R4.0.3, and Rapid miner were utilized for implementation. RESULTS: Our findings indicated that zinc, Iron, Niacin, Potassium, Phosphorous, and Cooper have a beneficial impact in reducing the risk of cervical cancer and progression of phase in Iranian women, as well as Salt, snacks and milk Were identified as high-risk food factors (P value < 0.05 and coefficient correlation > 0.6). Also, alcohol, and sex patient with two groups, HPV positive have an impact on cervical cancer incidence. Phosphorus and selenium in the Micronutrients category (R(2) = 0.85, AUC = 0.993) and polyunsaturated fatty acid and salt in the Macronutrients category and other categories of nutrients were identified as the most effective factors in cervical cancer using deep learning (R(2) = 0.93, AUC = 0.999). CONCLUSIONS: A diet and rich nutrition can be helpful for the prevention of cervix cancer and may reduce the risk of disease. Additional research is necessary for different countries. BioMed Central 2023-07-06 /pmc/articles/PMC10324228/ /pubmed/37415218 http://dx.doi.org/10.1186/s13027-023-00517-8 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Nazari, Elham Hasanzadeh, Malihe Rezvani, Reza Rejali, Marzieh Badpeyma, Mohaddeseh Delaram, Zeinab Mousavi-Seresht, Leila Akbari, Mahdieh Khazaei, Majid Ferns, Gordon A. Avan, Amir Association of dietary intake and cervical cancer: a prevention strategy |
title | Association of dietary intake and cervical cancer: a prevention strategy |
title_full | Association of dietary intake and cervical cancer: a prevention strategy |
title_fullStr | Association of dietary intake and cervical cancer: a prevention strategy |
title_full_unstemmed | Association of dietary intake and cervical cancer: a prevention strategy |
title_short | Association of dietary intake and cervical cancer: a prevention strategy |
title_sort | association of dietary intake and cervical cancer: a prevention strategy |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324228/ https://www.ncbi.nlm.nih.gov/pubmed/37415218 http://dx.doi.org/10.1186/s13027-023-00517-8 |
work_keys_str_mv | AT nazarielham associationofdietaryintakeandcervicalcancerapreventionstrategy AT hasanzadehmalihe associationofdietaryintakeandcervicalcancerapreventionstrategy AT rezvanireza associationofdietaryintakeandcervicalcancerapreventionstrategy AT rejalimarzieh associationofdietaryintakeandcervicalcancerapreventionstrategy AT badpeymamohaddeseh associationofdietaryintakeandcervicalcancerapreventionstrategy AT delaramzeinab associationofdietaryintakeandcervicalcancerapreventionstrategy AT mousavisereshtleila associationofdietaryintakeandcervicalcancerapreventionstrategy AT akbarimahdieh associationofdietaryintakeandcervicalcancerapreventionstrategy AT khazaeimajid associationofdietaryintakeandcervicalcancerapreventionstrategy AT fernsgordona associationofdietaryintakeandcervicalcancerapreventionstrategy AT avanamir associationofdietaryintakeandcervicalcancerapreventionstrategy |