Minimal change disease with papillary thyroid carcinoma: a report of two adult cases

BACKGROUND: Minimal change disease (MCD), a pathological type of nephrotic syndrome (NS), can occur in patients with tumors. We report two adult cases of MCD associated with papillary thyroid carcinoma (PTC), known to be extremely rare in adults. CASE PRESENTATION: A 35-year-old female patient was s...

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Autores principales: Yin, Juanjuan, Li, Zexuan, Hao, Zedong, Yu, Zhuanzhuan, Yu, Weimin, Yang, Guang, Ren, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324232/
https://www.ncbi.nlm.nih.gov/pubmed/37407942
http://dx.doi.org/10.1186/s12882-023-03252-9
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author Yin, Juanjuan
Li, Zexuan
Hao, Zedong
Yu, Zhuanzhuan
Yu, Weimin
Yang, Guang
Ren, Xiaojun
author_facet Yin, Juanjuan
Li, Zexuan
Hao, Zedong
Yu, Zhuanzhuan
Yu, Weimin
Yang, Guang
Ren, Xiaojun
author_sort Yin, Juanjuan
collection PubMed
description BACKGROUND: Minimal change disease (MCD), a pathological type of nephrotic syndrome (NS), can occur in patients with tumors. We report two adult cases of MCD associated with papillary thyroid carcinoma (PTC), known to be extremely rare in adults. CASE PRESENTATION: A 35-year-old female patient was simultaneously diagnosed with MCD and PTC. The MCD was effectively treated with thyroidectomy and prednisone.In addition, a 50-year-old male patient, who had been diagnosed with PTC three years prior, had MCD confirmed by renal biopsy. The patient achieved complete remission following treatment with tacrolimus and rituximab. CONCLUSIONS: The present case report describes and discusses the diagnostic and treatment processes employed in these two patients. Clinicians need to be aware of the renal effects of treating patients with solid tumors.
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spelling pubmed-103242322023-07-07 Minimal change disease with papillary thyroid carcinoma: a report of two adult cases Yin, Juanjuan Li, Zexuan Hao, Zedong Yu, Zhuanzhuan Yu, Weimin Yang, Guang Ren, Xiaojun BMC Nephrol Case Report BACKGROUND: Minimal change disease (MCD), a pathological type of nephrotic syndrome (NS), can occur in patients with tumors. We report two adult cases of MCD associated with papillary thyroid carcinoma (PTC), known to be extremely rare in adults. CASE PRESENTATION: A 35-year-old female patient was simultaneously diagnosed with MCD and PTC. The MCD was effectively treated with thyroidectomy and prednisone.In addition, a 50-year-old male patient, who had been diagnosed with PTC three years prior, had MCD confirmed by renal biopsy. The patient achieved complete remission following treatment with tacrolimus and rituximab. CONCLUSIONS: The present case report describes and discusses the diagnostic and treatment processes employed in these two patients. Clinicians need to be aware of the renal effects of treating patients with solid tumors. BioMed Central 2023-07-05 /pmc/articles/PMC10324232/ /pubmed/37407942 http://dx.doi.org/10.1186/s12882-023-03252-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Yin, Juanjuan
Li, Zexuan
Hao, Zedong
Yu, Zhuanzhuan
Yu, Weimin
Yang, Guang
Ren, Xiaojun
Minimal change disease with papillary thyroid carcinoma: a report of two adult cases
title Minimal change disease with papillary thyroid carcinoma: a report of two adult cases
title_full Minimal change disease with papillary thyroid carcinoma: a report of two adult cases
title_fullStr Minimal change disease with papillary thyroid carcinoma: a report of two adult cases
title_full_unstemmed Minimal change disease with papillary thyroid carcinoma: a report of two adult cases
title_short Minimal change disease with papillary thyroid carcinoma: a report of two adult cases
title_sort minimal change disease with papillary thyroid carcinoma: a report of two adult cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324232/
https://www.ncbi.nlm.nih.gov/pubmed/37407942
http://dx.doi.org/10.1186/s12882-023-03252-9
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