MicroRNA‐128 suppresses tau phosphorylation and reduces amyloid‐beta accumulation by inhibiting the expression of GSK3β, APPBP2, and mTOR in Alzheimer's disease

INTRODUCTION AND AIMS: Alzheimer's disease (AD) is characterized by the abnormal accumulation of hyperphosphorylated tau proteins and amyloid‐beta (Aβ) peptides. Recent studies have shown that many microRNAs (miRNAs) are dysregulated in AD, and modulation of these miRNAs can influence the devel...

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Detalles Bibliográficos
Autores principales: Li, Siwen, Poon, Chi Him, Zhang, Zhigang, Yue, Ming, Chen, Ruijun, Zhang, Yalun, Hossain, Md. Farhad, Pan, Yining, Zhao, Jun, Rong, Lei, Chu, Leung Wing, Shea, Yat Fung, Rogaeva, Ekaterina, Tu, Jie, St George‐Hyslop, Peter, Lim, Lee Wei, Song, You‐Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324361/
https://www.ncbi.nlm.nih.gov/pubmed/36880288
http://dx.doi.org/10.1111/cns.14143

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