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MicroRNA‐128 suppresses tau phosphorylation and reduces amyloid‐beta accumulation by inhibiting the expression of GSK3β, APPBP2, and mTOR in Alzheimer's disease
INTRODUCTION AND AIMS: Alzheimer's disease (AD) is characterized by the abnormal accumulation of hyperphosphorylated tau proteins and amyloid‐beta (Aβ) peptides. Recent studies have shown that many microRNAs (miRNAs) are dysregulated in AD, and modulation of these miRNAs can influence the devel...
Autores principales: | Li, Siwen, Poon, Chi Him, Zhang, Zhigang, Yue, Ming, Chen, Ruijun, Zhang, Yalun, Hossain, Md. Farhad, Pan, Yining, Zhao, Jun, Rong, Lei, Chu, Leung Wing, Shea, Yat Fung, Rogaeva, Ekaterina, Tu, Jie, St George‐Hyslop, Peter, Lim, Lee Wei, Song, You‐Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324361/ https://www.ncbi.nlm.nih.gov/pubmed/36880288 http://dx.doi.org/10.1111/cns.14143 |
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