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Propionic Acid Groups and Multiple Aromatic Rings Induce Binding of Ketoprofen and Naproxen to the Hydrophobic Core of Bovine Serum Albumin

[Image: see text] Ketoprofen (KP), which causes photosensitivity by interacting with serum albumin (SA), and three drugs, ibuprofen (IBP), naproxen (NPX), and diazepam (DZP), which share the same binding site, were investigated for their interaction with bovine SA (BSA). For KP, DZP, and IBP, where...

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Detalles Bibliográficos
Autores principales: Tsurushima, Minori, Kurosawa, Yuya, Goto, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324393/
https://www.ncbi.nlm.nih.gov/pubmed/37337436
http://dx.doi.org/10.1021/acs.molpharmaceut.3c00169