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New Radiolabeled Exendin Analogues Show Reduced Renal Retention

[Image: see text] PET imaging of the glucagon-like peptide-1 receptor (GLP-1R) using radiolabeled exendin is a promising imaging method to detect insulinomas. However, high renal accumulation of radiolabeled exendin could hamper the detection of small insulinomas in proximity to the kidneys and limi...

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Detalles Bibliográficos
Autores principales: Joosten, Lieke, Frielink, Cathelijne, Jansen, Theodorus J. P., Lobeek, Daphne, Andreae, Fritz, Konijnenberg, Mark, Heskamp, Sandra, Gotthardt, Martin, Brom, Maarten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324399/
https://www.ncbi.nlm.nih.gov/pubmed/37265006
http://dx.doi.org/10.1021/acs.molpharmaceut.3c00117