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Extended Detection Window for Gamma-Hydroxybutyrate in the Urine of an Elderly Woman

Gamma-hydroxybutyrate (GHB) is a central nervous system depressant that has gained popularity as an illicit recreational drug. We describe a case of an elderly woman who was found unconscious in her home. The paramedics initially suspected an intracranial incident. A head computed tomography was neg...

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Detalles Bibliográficos
Autores principales: Berg, J A, Rajendiran, R, Serkland, T T, Methlie, C B, Hallin, E I, Stokes, C L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324544/
https://www.ncbi.nlm.nih.gov/pubmed/36847150
http://dx.doi.org/10.1093/jat/bkad014
Descripción
Sumario:Gamma-hydroxybutyrate (GHB) is a central nervous system depressant that has gained popularity as an illicit recreational drug. We describe a case of an elderly woman who was found unconscious in her home. The paramedics initially suspected an intracranial incident. A head computed tomography was negative, as was the initial urinary drug screening. The diagnosis of GHB intoxication was made with the detection of GHB in a urine sample obtained 28–29 hours after the assumed time of intake. Our case underscores the importance of considering drug testing in a broad range of patients and shows that elderly patients may have an extended detection window of GHB.