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Correlation of finger-to-floor distance with the spinal mobility, spinal function indices and initial determination of its optimal cutoff value: a multicentre case–control study
OBJECTIVE: To identify the correlation between finger-to-floor distance(FFD) and the spinal function indices and disease activity scores of ankylosing spondylitis (AS) via a multicentre case–control study, and to calculate the optimal cutoff value of FFD using statistical methods. METHODS: Patients...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324647/ https://www.ncbi.nlm.nih.gov/pubmed/37425308 http://dx.doi.org/10.3389/fmed.2023.1135748 |
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author | Guo, Genggeng Zhang, Yulu Lin, Diantian Chen, Zhihan Yan, Qing Gao, Fei Wu, Yanfang He, Juanjuan Chen, Da Xie, Zugang Huang, Feng Zhang, Shengli |
author_facet | Guo, Genggeng Zhang, Yulu Lin, Diantian Chen, Zhihan Yan, Qing Gao, Fei Wu, Yanfang He, Juanjuan Chen, Da Xie, Zugang Huang, Feng Zhang, Shengli |
author_sort | Guo, Genggeng |
collection | PubMed |
description | OBJECTIVE: To identify the correlation between finger-to-floor distance(FFD) and the spinal function indices and disease activity scores of ankylosing spondylitis (AS) via a multicentre case–control study, and to calculate the optimal cutoff value of FFD using statistical methods. METHODS: Patients with AS and healthy individuals were recruited, and the FFD and other spinal mobility values were measured. The correlation between the FFD and the Bath Ankylosing Spondylitis Metric Index (BASMI), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI) was analyzed using Spearman rank correlation analysis. Receiver operating characteristic (ROC) curves of FFD stratified by gender and age were drawn and their optimal cutoff values were determined. RESULTS: A total of 246 patients with AS and 246 healthy subjects were recruited. The FFD was strongly correlated with BASMI (r = 0.72, p < 0.001), moderately correlated with BASFI (r = 0.50, p < 0.001) and weakly correlated with BASDAI (r = 0.36, p < 0.001). The lowest cutoff value of the FFD was 2.6 cm while the highest was 18.4 cm. Moreover, the FFD was significantly correlated with sex and age. CONCLUSION: There exists a strong correlation between the FFD and spinal mobility, a moderately correlation and function, which provides reliable data for the evaluation of patients with AS in clinical settings and the rapid screening of low back pain-related diseases in the general population. Furthermore, these findings have clinical potential in improving the missed diagnosis or delayed diagnosis of low back pain. |
format | Online Article Text |
id | pubmed-10324647 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-103246472023-07-07 Correlation of finger-to-floor distance with the spinal mobility, spinal function indices and initial determination of its optimal cutoff value: a multicentre case–control study Guo, Genggeng Zhang, Yulu Lin, Diantian Chen, Zhihan Yan, Qing Gao, Fei Wu, Yanfang He, Juanjuan Chen, Da Xie, Zugang Huang, Feng Zhang, Shengli Front Med (Lausanne) Medicine OBJECTIVE: To identify the correlation between finger-to-floor distance(FFD) and the spinal function indices and disease activity scores of ankylosing spondylitis (AS) via a multicentre case–control study, and to calculate the optimal cutoff value of FFD using statistical methods. METHODS: Patients with AS and healthy individuals were recruited, and the FFD and other spinal mobility values were measured. The correlation between the FFD and the Bath Ankylosing Spondylitis Metric Index (BASMI), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI) was analyzed using Spearman rank correlation analysis. Receiver operating characteristic (ROC) curves of FFD stratified by gender and age were drawn and their optimal cutoff values were determined. RESULTS: A total of 246 patients with AS and 246 healthy subjects were recruited. The FFD was strongly correlated with BASMI (r = 0.72, p < 0.001), moderately correlated with BASFI (r = 0.50, p < 0.001) and weakly correlated with BASDAI (r = 0.36, p < 0.001). The lowest cutoff value of the FFD was 2.6 cm while the highest was 18.4 cm. Moreover, the FFD was significantly correlated with sex and age. CONCLUSION: There exists a strong correlation between the FFD and spinal mobility, a moderately correlation and function, which provides reliable data for the evaluation of patients with AS in clinical settings and the rapid screening of low back pain-related diseases in the general population. Furthermore, these findings have clinical potential in improving the missed diagnosis or delayed diagnosis of low back pain. Frontiers Media S.A. 2023-06-22 /pmc/articles/PMC10324647/ /pubmed/37425308 http://dx.doi.org/10.3389/fmed.2023.1135748 Text en Copyright © 2023 Guo, Zhang, Lin, Chen, Yan, Gao, Wu, He, Chen, Xie, Huang and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Guo, Genggeng Zhang, Yulu Lin, Diantian Chen, Zhihan Yan, Qing Gao, Fei Wu, Yanfang He, Juanjuan Chen, Da Xie, Zugang Huang, Feng Zhang, Shengli Correlation of finger-to-floor distance with the spinal mobility, spinal function indices and initial determination of its optimal cutoff value: a multicentre case–control study |
title | Correlation of finger-to-floor distance with the spinal mobility, spinal function indices and initial determination of its optimal cutoff value: a multicentre case–control study |
title_full | Correlation of finger-to-floor distance with the spinal mobility, spinal function indices and initial determination of its optimal cutoff value: a multicentre case–control study |
title_fullStr | Correlation of finger-to-floor distance with the spinal mobility, spinal function indices and initial determination of its optimal cutoff value: a multicentre case–control study |
title_full_unstemmed | Correlation of finger-to-floor distance with the spinal mobility, spinal function indices and initial determination of its optimal cutoff value: a multicentre case–control study |
title_short | Correlation of finger-to-floor distance with the spinal mobility, spinal function indices and initial determination of its optimal cutoff value: a multicentre case–control study |
title_sort | correlation of finger-to-floor distance with the spinal mobility, spinal function indices and initial determination of its optimal cutoff value: a multicentre case–control study |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324647/ https://www.ncbi.nlm.nih.gov/pubmed/37425308 http://dx.doi.org/10.3389/fmed.2023.1135748 |
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