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Ischemic Vaso-occlusive Retinopathy as Initial Presentation in Pediatric Systemic Lupus Erythematosus: A Case Report
Ischemic vaso-occlusive retinopathy as an initial manifestation is rare in pediatric systemic lupus erythematosus (pSLE). A 13-year-old girl presented with two months’ history of papules and crusts with fatigue, weight loss, and abrupt hair loss. Pancytopenia and findings compatible with SLE, includ...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Korean College of Rheumatology
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324919/ https://www.ncbi.nlm.nih.gov/pubmed/37476696 http://dx.doi.org/10.4078/jrd.2022.29.1.52 |
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author | Jeon, Jin Hwan Choi, Hye Yeon Rhim, Jung Woo Lee, Soo Young Park, Young Gun Jeong, Dae Chul |
author_facet | Jeon, Jin Hwan Choi, Hye Yeon Rhim, Jung Woo Lee, Soo Young Park, Young Gun Jeong, Dae Chul |
author_sort | Jeon, Jin Hwan |
collection | PubMed |
description | Ischemic vaso-occlusive retinopathy as an initial manifestation is rare in pediatric systemic lupus erythematosus (pSLE). A 13-year-old girl presented with two months’ history of papules and crusts with fatigue, weight loss, and abrupt hair loss. Pancytopenia and findings compatible with SLE, including positive direct Coombs’ test, antinuclear antibody (Ab), anti-double stranded DNA Ab, anti-Smith Ab, anti-ribonucleoprotein Ab, lupus anticoagulant, anti-β2 glycoprotein Immunoglobulin G, and anti-cardiolipin Ab, were detected. Bi-nasal hemianopsia was detected. Initial visual acuity was hand motion in the right eye and 15/20 in the left. Fundoscopy showed massive exudation around the optic disc with macular edema, vascular sheathing with perivascular hemorrhage in the whole retina, and ghost vessels in the peripheral retina. Intravitreal triamcinolone injection and dexamethasone implant injection were administered. Visual symptoms improved but did not recover. Methylprednisolone therapy and photocoagulation improved visual acuity and fever. Early intervention for retinopathy in pSLE can help prevent vision-loss. |
format | Online Article Text |
id | pubmed-10324919 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Korean College of Rheumatology |
record_format | MEDLINE/PubMed |
spelling | pubmed-103249192023-07-20 Ischemic Vaso-occlusive Retinopathy as Initial Presentation in Pediatric Systemic Lupus Erythematosus: A Case Report Jeon, Jin Hwan Choi, Hye Yeon Rhim, Jung Woo Lee, Soo Young Park, Young Gun Jeong, Dae Chul J Rheum Dis Case Report Ischemic vaso-occlusive retinopathy as an initial manifestation is rare in pediatric systemic lupus erythematosus (pSLE). A 13-year-old girl presented with two months’ history of papules and crusts with fatigue, weight loss, and abrupt hair loss. Pancytopenia and findings compatible with SLE, including positive direct Coombs’ test, antinuclear antibody (Ab), anti-double stranded DNA Ab, anti-Smith Ab, anti-ribonucleoprotein Ab, lupus anticoagulant, anti-β2 glycoprotein Immunoglobulin G, and anti-cardiolipin Ab, were detected. Bi-nasal hemianopsia was detected. Initial visual acuity was hand motion in the right eye and 15/20 in the left. Fundoscopy showed massive exudation around the optic disc with macular edema, vascular sheathing with perivascular hemorrhage in the whole retina, and ghost vessels in the peripheral retina. Intravitreal triamcinolone injection and dexamethasone implant injection were administered. Visual symptoms improved but did not recover. Methylprednisolone therapy and photocoagulation improved visual acuity and fever. Early intervention for retinopathy in pSLE can help prevent vision-loss. Korean College of Rheumatology 2022-01-01 2022-01-01 /pmc/articles/PMC10324919/ /pubmed/37476696 http://dx.doi.org/10.4078/jrd.2022.29.1.52 Text en Copyright © 2022 by The Korean College of Rheumatology. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Jeon, Jin Hwan Choi, Hye Yeon Rhim, Jung Woo Lee, Soo Young Park, Young Gun Jeong, Dae Chul Ischemic Vaso-occlusive Retinopathy as Initial Presentation in Pediatric Systemic Lupus Erythematosus: A Case Report |
title | Ischemic Vaso-occlusive Retinopathy as Initial Presentation in Pediatric Systemic Lupus Erythematosus: A Case Report |
title_full | Ischemic Vaso-occlusive Retinopathy as Initial Presentation in Pediatric Systemic Lupus Erythematosus: A Case Report |
title_fullStr | Ischemic Vaso-occlusive Retinopathy as Initial Presentation in Pediatric Systemic Lupus Erythematosus: A Case Report |
title_full_unstemmed | Ischemic Vaso-occlusive Retinopathy as Initial Presentation in Pediatric Systemic Lupus Erythematosus: A Case Report |
title_short | Ischemic Vaso-occlusive Retinopathy as Initial Presentation in Pediatric Systemic Lupus Erythematosus: A Case Report |
title_sort | ischemic vaso-occlusive retinopathy as initial presentation in pediatric systemic lupus erythematosus: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324919/ https://www.ncbi.nlm.nih.gov/pubmed/37476696 http://dx.doi.org/10.4078/jrd.2022.29.1.52 |
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