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Ischemic Vaso-occlusive Retinopathy as Initial Presentation in Pediatric Systemic Lupus Erythematosus: A Case Report

Ischemic vaso-occlusive retinopathy as an initial manifestation is rare in pediatric systemic lupus erythematosus (pSLE). A 13-year-old girl presented with two months’ history of papules and crusts with fatigue, weight loss, and abrupt hair loss. Pancytopenia and findings compatible with SLE, includ...

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Autores principales: Jeon, Jin Hwan, Choi, Hye Yeon, Rhim, Jung Woo, Lee, Soo Young, Park, Young Gun, Jeong, Dae Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean College of Rheumatology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324919/
https://www.ncbi.nlm.nih.gov/pubmed/37476696
http://dx.doi.org/10.4078/jrd.2022.29.1.52
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author Jeon, Jin Hwan
Choi, Hye Yeon
Rhim, Jung Woo
Lee, Soo Young
Park, Young Gun
Jeong, Dae Chul
author_facet Jeon, Jin Hwan
Choi, Hye Yeon
Rhim, Jung Woo
Lee, Soo Young
Park, Young Gun
Jeong, Dae Chul
author_sort Jeon, Jin Hwan
collection PubMed
description Ischemic vaso-occlusive retinopathy as an initial manifestation is rare in pediatric systemic lupus erythematosus (pSLE). A 13-year-old girl presented with two months’ history of papules and crusts with fatigue, weight loss, and abrupt hair loss. Pancytopenia and findings compatible with SLE, including positive direct Coombs’ test, antinuclear antibody (Ab), anti-double stranded DNA Ab, anti-Smith Ab, anti-ribonucleoprotein Ab, lupus anticoagulant, anti-β2 glycoprotein Immunoglobulin G, and anti-cardiolipin Ab, were detected. Bi-nasal hemianopsia was detected. Initial visual acuity was hand motion in the right eye and 15/20 in the left. Fundoscopy showed massive exudation around the optic disc with macular edema, vascular sheathing with perivascular hemorrhage in the whole retina, and ghost vessels in the peripheral retina. Intravitreal triamcinolone injection and dexamethasone implant injection were administered. Visual symptoms improved but did not recover. Methylprednisolone therapy and photocoagulation improved visual acuity and fever. Early intervention for retinopathy in pSLE can help prevent vision-loss.
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spelling pubmed-103249192023-07-20 Ischemic Vaso-occlusive Retinopathy as Initial Presentation in Pediatric Systemic Lupus Erythematosus: A Case Report Jeon, Jin Hwan Choi, Hye Yeon Rhim, Jung Woo Lee, Soo Young Park, Young Gun Jeong, Dae Chul J Rheum Dis Case Report Ischemic vaso-occlusive retinopathy as an initial manifestation is rare in pediatric systemic lupus erythematosus (pSLE). A 13-year-old girl presented with two months’ history of papules and crusts with fatigue, weight loss, and abrupt hair loss. Pancytopenia and findings compatible with SLE, including positive direct Coombs’ test, antinuclear antibody (Ab), anti-double stranded DNA Ab, anti-Smith Ab, anti-ribonucleoprotein Ab, lupus anticoagulant, anti-β2 glycoprotein Immunoglobulin G, and anti-cardiolipin Ab, were detected. Bi-nasal hemianopsia was detected. Initial visual acuity was hand motion in the right eye and 15/20 in the left. Fundoscopy showed massive exudation around the optic disc with macular edema, vascular sheathing with perivascular hemorrhage in the whole retina, and ghost vessels in the peripheral retina. Intravitreal triamcinolone injection and dexamethasone implant injection were administered. Visual symptoms improved but did not recover. Methylprednisolone therapy and photocoagulation improved visual acuity and fever. Early intervention for retinopathy in pSLE can help prevent vision-loss. Korean College of Rheumatology 2022-01-01 2022-01-01 /pmc/articles/PMC10324919/ /pubmed/37476696 http://dx.doi.org/10.4078/jrd.2022.29.1.52 Text en Copyright © 2022 by The Korean College of Rheumatology. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Jeon, Jin Hwan
Choi, Hye Yeon
Rhim, Jung Woo
Lee, Soo Young
Park, Young Gun
Jeong, Dae Chul
Ischemic Vaso-occlusive Retinopathy as Initial Presentation in Pediatric Systemic Lupus Erythematosus: A Case Report
title Ischemic Vaso-occlusive Retinopathy as Initial Presentation in Pediatric Systemic Lupus Erythematosus: A Case Report
title_full Ischemic Vaso-occlusive Retinopathy as Initial Presentation in Pediatric Systemic Lupus Erythematosus: A Case Report
title_fullStr Ischemic Vaso-occlusive Retinopathy as Initial Presentation in Pediatric Systemic Lupus Erythematosus: A Case Report
title_full_unstemmed Ischemic Vaso-occlusive Retinopathy as Initial Presentation in Pediatric Systemic Lupus Erythematosus: A Case Report
title_short Ischemic Vaso-occlusive Retinopathy as Initial Presentation in Pediatric Systemic Lupus Erythematosus: A Case Report
title_sort ischemic vaso-occlusive retinopathy as initial presentation in pediatric systemic lupus erythematosus: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324919/
https://www.ncbi.nlm.nih.gov/pubmed/37476696
http://dx.doi.org/10.4078/jrd.2022.29.1.52
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