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The Mechanism of the NLRP3 Inflammasome Activation and Pathogenic Implication in the Pathogenesis of Gout
The NACHT, LRR, and PYD-domains-containing protein 3 (NLRP3) inflammasome is an intracellular multi-protein signaling platform that is activated by cytosolic pattern-recognition receptors such as NLRs against endogenous and exogenous pathogens. Once it is activated by a variety of danger signals, re...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Korean College of Rheumatology
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324924/ https://www.ncbi.nlm.nih.gov/pubmed/37475970 http://dx.doi.org/10.4078/jrd.2022.29.3.140 |