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Epidemiology and treatment-related concerns of gout and hyperuricemia in Korean

Gout is the most common form of inflammatory arthritis that affects mainly middle-aged men, and there is clear evidence of an association between hyperuricemia and the risk for gout. Increasing prevalence of gout and hyperuricemia has been reported in many countries. The prevalence of gout and hyper...

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Autor principal: Ahn, Joong Kyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean College of Rheumatology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324937/
https://www.ncbi.nlm.nih.gov/pubmed/37483480
http://dx.doi.org/10.4078/jrd.2022.0001
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author Ahn, Joong Kyong
author_facet Ahn, Joong Kyong
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description Gout is the most common form of inflammatory arthritis that affects mainly middle-aged men, and there is clear evidence of an association between hyperuricemia and the risk for gout. Increasing prevalence of gout and hyperuricemia has been reported in many countries. The prevalence of gout and hyperuricemia are constantly increasing in Korea with the patients at risk for developing a variety of comorbidities. Although there have been studies on the association between gout or serum uric acid level and several neurodegenerative diseases, cancer, and cardiovascular mortality, the causal relationship between gout and these comorbidities are still unclear. The associations of substantial economic burden with hyperuricemia, gout attack, and suboptimal treatment are well known. Gout is a disease that requires lifelong management including lifestyle modification. However, gout is poorly managed worldwide although effective urate-lowering drugs exist. In this review, we addressed epidemiological studies and treatment-related problems in the Korean population with gout or hyperuricemia to obtain the best clinical outcomes and reduce their medical burden.
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spelling pubmed-103249372023-07-21 Epidemiology and treatment-related concerns of gout and hyperuricemia in Korean Ahn, Joong Kyong J Rheum Dis Review Article Gout is the most common form of inflammatory arthritis that affects mainly middle-aged men, and there is clear evidence of an association between hyperuricemia and the risk for gout. Increasing prevalence of gout and hyperuricemia has been reported in many countries. The prevalence of gout and hyperuricemia are constantly increasing in Korea with the patients at risk for developing a variety of comorbidities. Although there have been studies on the association between gout or serum uric acid level and several neurodegenerative diseases, cancer, and cardiovascular mortality, the causal relationship between gout and these comorbidities are still unclear. The associations of substantial economic burden with hyperuricemia, gout attack, and suboptimal treatment are well known. Gout is a disease that requires lifelong management including lifestyle modification. However, gout is poorly managed worldwide although effective urate-lowering drugs exist. In this review, we addressed epidemiological studies and treatment-related problems in the Korean population with gout or hyperuricemia to obtain the best clinical outcomes and reduce their medical burden. Korean College of Rheumatology 2023-04-01 2023-03-17 /pmc/articles/PMC10324937/ /pubmed/37483480 http://dx.doi.org/10.4078/jrd.2022.0001 Text en Copyright © 2023 by The Korean College of Rheumatology. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Ahn, Joong Kyong
Epidemiology and treatment-related concerns of gout and hyperuricemia in Korean
title Epidemiology and treatment-related concerns of gout and hyperuricemia in Korean
title_full Epidemiology and treatment-related concerns of gout and hyperuricemia in Korean
title_fullStr Epidemiology and treatment-related concerns of gout and hyperuricemia in Korean
title_full_unstemmed Epidemiology and treatment-related concerns of gout and hyperuricemia in Korean
title_short Epidemiology and treatment-related concerns of gout and hyperuricemia in Korean
title_sort epidemiology and treatment-related concerns of gout and hyperuricemia in korean
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324937/
https://www.ncbi.nlm.nih.gov/pubmed/37483480
http://dx.doi.org/10.4078/jrd.2022.0001
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