Genetic regulators of sputum mucin concentration and their associations with COPD phenotypes

Hyper-secretion and/or hyper-concentration of mucus is a defining feature of multiple obstructive lung diseases, including chronic obstructive pulmonary disease (COPD). Mucus itself is composed of a mixture of water, ions, salt and proteins, of which the gel-forming mucins, MUC5AC and MUC5B, are the...

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Detalles Bibliográficos
Autores principales: Van Buren, Eric, Radicioni, Giorgia, Lester, Sarah, O’Neal, Wanda K., Dang, Hong, Kasela, Silva, Garudadri, Suresh, Curtis, Jeffrey L., Han, MeiLan K., Krishnan, Jerry A., Wan, Emily S., Silverman, Edwin K., Hastie, Annette, Ortega, Victor E., Lappalainen, Tuuli, Nawijn, Martijn C., van den Berge, Maarten, Christenson, Stephanie A., Li, Yun, Cho, Michael H., Kesimer, Mehmet, Kelada, Samir N. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325042/
https://www.ncbi.nlm.nih.gov/pubmed/37352370
http://dx.doi.org/10.1371/journal.pgen.1010445

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