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TRIM21 restricts influenza A virus replication by ubiquitination-dependent degradation of M1

Tripartite motif-containing protein 21 (TRIM21), an E3 ubiquitin ligase, plays a critical role in the host antiviral response. However, the mechanism and antiviral spectrum of TRIM21 in influenza A virus (IAV) remain unclear. Here, we report that TRIM21 inhibits the replication of various IAV subtyp...

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Detalles Bibliográficos
Autores principales:	Lin, Lulu, Wang, Xingbo, Chen, Zhen, Deng, Tingjuan, Yan, Yan, Dong, Weiren, Huang, Yu, Zhou, Jiyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325077/ https://www.ncbi.nlm.nih.gov/pubmed/37343022 http://dx.doi.org/10.1371/journal.ppat.1011472

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