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Tissue-specific reprogramming of glutamine metabolism maintains tolerance to sepsis
Reprogramming metabolism is of great therapeutic interest for reducing morbidity and mortality during sepsis-induced critical illness. Disappointing results from randomized controlled trials targeting glutamine and antioxidant metabolism in patients with sepsis have begged a deeper understanding of...
Autores principales: | Leitner, Brooks P., Lee, Won D., Zhu, Wanling, Zhang, Xinyi, Gaspar, Rafael C., Li, Zongyu, Rabinowitz, Joshua D., Perry, Rachel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325078/ https://www.ncbi.nlm.nih.gov/pubmed/37410734 http://dx.doi.org/10.1371/journal.pone.0286525 |
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