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Targeted treatment in a case series of AR+, HRAS/PIK3CA co-mutated salivary duct carcinoma

BACKGROUND AND PURPOSE: A subgroup of salivary duct carcinoma (SDC) harbor overexpression of the androgen receptor (AR), and co-occurring mutations in the HRAS- and PIK3CA-genes. The impact of genomic complexity on targeted treatment strategies in advanced cancer is unknown. MATERIALS AND METHODS: W...

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Detalles Bibliográficos
Autores principales:	Rieke, Damian T., Schröder, Sebastian, Schafhausen, Philippe, Blanc, Eric, Zuljan, Erika, von der Emde, Benjamin, Beule, Dieter, Keller, Ulrich, Keilholz, Ulrich, Klinghammer, Konrad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325704/ https://www.ncbi.nlm.nih.gov/pubmed/37427101 http://dx.doi.org/10.3389/fonc.2023.1107134

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