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The ER folding sensor UGGT1 acts on TAPBPR-chaperoned peptide-free MHC I

Adaptive immune responses are triggered by antigenic peptides presented on major histocompatibility complex class I (MHC I) at the surface of pathogen-infected or cancerous cells. Formation of stable peptide-MHC I complexes is facilitated by tapasin and TAPBPR, two related MHC I-specific chaperones...

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Detalles Bibliográficos
Autores principales:	Sagert, Lina, Winter, Christian, Ruppert, Ina, Zehetmaier, Maximilian, Thomas, Christoph, Tampé, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2023
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325711/ https://www.ncbi.nlm.nih.gov/pubmed/37345806 http://dx.doi.org/10.7554/eLife.85432

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