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Characteristics of Mycobacterium tuberculosis PtpA interaction and activity on the alpha subunit of human mitochondrial trifunctional protein, a key enzyme of lipid metabolism

During Mycobacterium tuberculosis (Mtb) infection, the virulence factor PtpA belonging to the protein tyrosine phosphatase family is delivered into the cytosol of the macrophage. PtpA interacts with numerous eukaryotic proteins modulating phagosome maturation, innate immune response, apoptosis, and...

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Detalles Bibliográficos
Autores principales: Margenat, Mariana, Betancour, Gabriela, Irving, Vivian, Costábile, Alicia, García-Cedrés, Tania, Portela, María Magdalena, Carrión, Federico, Herrera, Fernando E., Villarino, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325834/
https://www.ncbi.nlm.nih.gov/pubmed/37424790
http://dx.doi.org/10.3389/fcimb.2023.1095060

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