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Characteristics of Mycobacterium tuberculosis PtpA interaction and activity on the alpha subunit of human mitochondrial trifunctional protein, a key enzyme of lipid metabolism
During Mycobacterium tuberculosis (Mtb) infection, the virulence factor PtpA belonging to the protein tyrosine phosphatase family is delivered into the cytosol of the macrophage. PtpA interacts with numerous eukaryotic proteins modulating phagosome maturation, innate immune response, apoptosis, and...
Autores principales: | Margenat, Mariana, Betancour, Gabriela, Irving, Vivian, Costábile, Alicia, García-Cedrés, Tania, Portela, María Magdalena, Carrión, Federico, Herrera, Fernando E., Villarino, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325834/ https://www.ncbi.nlm.nih.gov/pubmed/37424790 http://dx.doi.org/10.3389/fcimb.2023.1095060 |
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